⚕️ Full Prescribing Information

For complete safety information, warnings, and dosage guidelines:

View FDA Label (PDF) →

📋 Overview

Tizanidine is a muscle relaxant used for spasticity in multiple sclerosis and spinal cord injuries. It has significant drug interactions and requires careful dosing.

How It Works

Tizanidine activates alpha-2 receptors in the spinal cord, reducing nerve signals that cause muscle spasms and spasticity.

✓ FDA Approved Uses

  • Muscle spasms
  • Spasticity from MS or spinal cord injury

⚡ Common Side Effects

Contact your doctor if these persist or worsen:

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Weakness
  • Fatigue
  • Low blood pressure

🚨 Serious Side Effects

Seek immediate medical attention if you experience:

  • Liver damage
  • Severe low blood pressure
  • Sedation
  • Hallucinations

⚠️ Do Not Use If

  • Allergy to tizanidine
  • Use with fluvoxamine or ciprofloxacin
  • Severe liver disease

📢 Important Warnings

  • Liver function monitoring needed
  • Sedation
  • Low blood pressure
  • Drug interactions

📚 Sources

Last Reviewed: December 1969