⚕️ Full Prescribing Information

For complete safety information, warnings, and dosage guidelines:

View FDA Label (PDF) →

📋 Overview

Ondansetron is a highly effective anti-nausea medication primarily used for chemotherapy and surgery patients. It works quickly and is generally well-tolerated.

How It Works

Ondansetron blocks 5-HT3 serotonin receptors in the gut and brain, preventing nausea and vomiting signals from triggering the vomiting center.

✓ FDA Approved Uses

  • Nausea and vomiting from chemotherapy
  • Nausea and vomiting after surgery
  • Nausea from radiation therapy

⚡ Common Side Effects

Contact your doctor if these persist or worsen:

  • Headache
  • Fatigue
  • Constipation
  • Diarrhea
  • Dizziness

🚨 Serious Side Effects

Seek immediate medical attention if you experience:

  • QT prolongation (heart rhythm)
  • Serotonin syndrome
  • Severe allergic reactions
  • Torsades de pointes

⚠️ Do Not Use If

  • Allergy to ondansetron
  • Congenital long QT syndrome
  • Concomitant apomorphine

📢 Important Warnings

  • Heart rhythm monitoring in high-risk patients
  • Serotonin syndrome with other serotonergic drugs
  • Not for routine morning sickness

📚 Sources

Last Reviewed: December 1969